It is soon going to be the Summer of Love Revisited, the smell of oxytocin, coming to a pharmacy near you, is in the air. Moreover, quite possibly a new baby boom if the effects of oxytocin on men are to be believed. Men could even breastfeed given a sufficient quantity of oxytocin taking some of the work off the women’s shoulders.  Not to mention more cuddle time with hubby. With all that empathy going on labor pains can be shared if not physically, mentally. Life gets curiouser and curiouser. As if not all these bons sentiments, (good feelings) are enough, oxytocin taken before meals three times a day can fat-guy-little-boatreduce your caloric intake by a whopping 122 calories in addition to 80 calories from fat. Is not this worth all the trouble? In addition, as an extra bonus the fee for taking this oxytocin based, they say, on European costs would be about $275 a month. What a monumental bust this is. Oxytocin is better marketed as a male tranquilizer then weight-loss product. Everything comes full circle. If you are going to use a drug for weight loss, nothing beats the amphetamines for efficacy and price. Nevertheless, remember as soon as you go off the drug your weight will most probably return and then some.

tim leary and neil cassidy
Timothy Leary and Neal Cassady (right)

Oh happy daze, the word is out, acid and shrooms are less harmful than alcohol and other controlled substances. Combine one of these two drugs with oxytocin and you have a good trip.  Old Richard Nixon gave LSD and psilocybin a bad rap back in the day. As paranoid as he was, he probably took some bad LSD and cried sour grapes.

Ken Kesey and Neal Cassady bare their chests during the Merry Pranksters' Acid Test Graduation
Ken Kesey and Neal Cassady bare their chests during the Merry Pranksters’ Acid Test Graduation

For all the good press these drugs are getting three caveats must be made.

  • There is such a thing as a bad trip, usually occurring in an unfamiliar place or if someone or something goes out of the way to scare the dickens out of you.
  • Poorly manufactured or adulterated LSD.
  • Hallucinogen persisting perception disorder, which are visual distortions or colored dots appearing in your vision: this disorder can occur with varying frequency for an extended period.
Kesey Bus "Further"
Kesey Bus “Further”

The last article deals with a brief bio of the Merry Pranksters. If you are interested in a more detailed biography look up the Merry Pranksters in Wikipedia. http://en.wikipedia.org/wiki/Merry_Pranksters.



Empire State Tribune

Journalism Comes First
Study, Oxytocin May Reduce Appetite, Making it a Safe and Highly Effective Weight Loss Tool

March 8, 2015

The new study tried a manufactured nasal formulation of oxytocin, and discovered the hormone treatment lessened the quantity of calories that men consumed, particularly calories from greasy foods.

The hormone oxytocin is connected to numerous exercises that bond individuals together, including sex, embracing, kissing, holding hands, and conceiving an offspring and breast feeding. In pharmaceutical, its utilized to induce labor, oversee bleeding in moms after conception and urge out breast milk in nursing women, Lawson said.

The analysts launched their study into oxytocin’s potential effects for consuming because research in animals has proposed that the hormone helps the body regulate body intake, she said. “Not much is known about oxytocin effects on appetite and food consumption in humans,” Lawson added.

In the new study, the scientists randomly appointed 25 men (12 of whom were overweight or obese) to either take synthetic oxytocin by means of nasal spread or an inactive placebo. The men did not know which spray they were given. The average age of the participants was 27, as per the study.

After taking either the hormone or placebo, the men requested breakfast from a menu. They were given twofold segments of whatever they requested. Toward the end of the meal, the specialists measured the amount of food consumed.

The men later returned and did the examination once more, yet this time they got the placebo in the event that they’d taken oxytocin the past time, or the reverse.

The individuals who took the oxytocin consumed 122 less calories, on average, the study found. They additionally ate less fatty food — around 9 less fat grams on average. That means around 80 less calories from fatty food.

Lawson said it’s not clear from this study how oxytocin influences the appetite.

Furthermore, there are a few admonitions to the study. The specialists didn’t think about if the men who consumed less were hungrier later, and ladies were excluded, so there’s no real way to know how they may be influenced.

While the men who took oxytocin didn’t have more side effects than the other men, “potential side effects with intranasal oxytocin include uterine contractions in pregnant women and, rarely, nausea, headache or allergic dermatitis,” Lawson said.

The nasal spray is affirmed for utilization in Europe, yet not in the United States. If utilized preceding meals three times each day, the expense of the medication — based on European costs — would be about $275 a month, Lawson said.

The study is little, and still ahead of schedule in the examination procedure, noted Paul Zak, founding director of the Center for Neuroeconomics Studies at Claremont Graduate University in California.

Still, he sees potential. “From an evolutionary perspective, oxytocin is released during positive social interactions — when we are around others who care about us. This is just when food sharing is likely to occur. If we want to lose weight, having others around us who care about us can help reduce appetite,” he suggested.



Study says Psychedelic Drug like LSD use doesn’t raise risk of Mental Health Problems

Posted on by Jamie Hacking





Latest studies have revealed that use of psychedelic drugs does not increase the risk of mental health problems. The study involved analysis of data from 135,000 randomly selected participants – including 19,000 people who had used drugs such as LSD and magic mushrooms.

The study showed that use of these Psychedelic drugs does not reveal any increased risk of developing mental health ailments later on in life.

Researchers from the Norwegian University of Science and Technology in Trondheim had also conducted a study earlier and had conducted population study investigating associations between mental health and psychedelic use. The study involved analysis of data in between 2001 to 2004.

Psychedelic Drug Like LSD Use Doesn't Raise Risk of Mental Health Problems, Study Says   

Author and clinical psychologist Pal-orjan Johansen says, “Over 30 million US adults have tried psychedelics and there just is not much evidence of health problems.”

Co-author and neuroscientist Teri Krebs feels, “Drug experts consistently rank LSD and psilocybin mushrooms as much less harmful to the individual user and to society compared to alcohol and other controlled substances.”

The study envisaged the study of data obtained from the US National Health Survey (2008-2011) consisting of 135,095 randomly selected adults from the US, including 19,299 users of psychedelic drugs.

The researchers did not find any link between the use of psychedelic drugs like LSD and magic mushrooms and symptoms of mental illness like psychological distress, depression, anxiety or suicidal thoughts, plans and attempts.

Krebs said, “Many people report deeply meaningful experiences and lasting beneficial effects from using psychedelics.”

However Johansen was quick to acknowledge the pitfalls of such studies and therefore considering the design and the mode of the study the researchers cannot rule out the negative effects of such drugs on certain individuals.

Johansen said, the researchers cannot “exclude the possibility that use of psychedelics might have a negative effect on mental health for some individuals or groups, perhaps counterbalanced at a population level by a positive effect on mental health in others.”

The details of the study are published in the Journal of Psychopharmacology.



Who Were the Merry Pranksters?

Ken Kesey, leader of the Merry Pranksters, was arrested for marijuana possession.
Ken Kesey, leader of the Merry Pranksters, was arrested for marijuana possession.

The original Merry Pranksters patterned their lifestyles on the experiences in Jack Kerouac's novel On The Road.
The original Merry Pranksters patterned their lifestyles on the experiences in Jack Kerouac’s novel On The Road

Written By: Michael Pollick

Edited By: Niki Foster

Images By: Atomazul, n/a

Last Modified Date: 01 February 2015

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Poets and writers such as Jack Kerouac and Allen Ginsberg defied mainstream society by publishing jazz-influenced works, often laced with drug references and obscene language. During the late 1950s, author Ken Kesey and several of his friends living in a Bohemian section of Stanford, California formed a loose alliance called the Merry Pranksters. The original Merry Pranksters patterned their lifestyles after the New York-based beatnik culture, especially the On the Road experiences of Jack Kerouac.

Around 1960, Ken Kesey volunteered for a series of medical experiments involving various psychedelic drugs, such as mescaline, peyote, morning glory seeds and most significantly, LSD. Kesey smuggled many of these substances back to the other Merry Pranksters, who later discovered legal methods for importing peyote from Mexico. Meanwhile, Kesey himself became a successful novelist with the publication of One Flew Over the Cuckoo’s Nest and Sometimes a Great Notion. Fueled by their mind-expanding drug experiences, the Merry Pranksters began to form grandiose ideas about turning on the rest of the country’s youth to LSD and other psychedelic drugs.

In 1964, Ken Kesey wanted to visit the New York City beatnik scene at the same time his novelSometimes a Great Notion would be published. To accomplish this cross-country trip, the Merry Pranksters bought a retired school bus and completely refurbished it. Inspired by the pop art of Andy Warhol and the comic book style of Roy Lichtenstein, the Merry Pranksters created numerous Day-Glo murals on both the interior and exterior walls. The bus also contained a number of film cameras and microphones, which the Merry Pranksters used to record nearly every second of their trip. Ken Kesey named the bus Further, perhaps referring to the mind-expanding effects of LSD.

The bus was driven primarily by Neal Cassady, a legendary counterculture figure made famous through Jack Kerouac’s writings. The plan was to drive around the United States with a large supply of LSD and other drugs. Visitors would be encouraged to ingest drug-laced juices and join the Merry Pranksters in street theater pranks or other improvised events. Since LSD was considered legal until 1966, law enforcement officers could not seize the bus or arrest its occupants for drug possession. This cross-country trip culminated in a fateful meeting with Jack Kerouac and several other Beat Generation leaders. Kerouac did not embrace the new counterculture generation, since many of their experiences were fueled by harder drugs than marijuana or alcohol.

After returning to California, the Merry Pranksters sponsored a series of parties designed to introduce LSD and other hallucinogens to the burgeoning hippie movement. These events were informally called Acid Tests, with signs asking “Can YOU pass the test?” The venues were painted in Day-Glo colors and featured the psychedelic artwork often associated with the Haight-Asbury hippie culture. Local bands were often hired to provide background music for the participants, with psychedelia-inspired names such as the Grateful Dead, Jefferson Airplane and the Doors.

After LSD became illegal in 1966, the Merry Pranksters suffered a tremendous blow. Fearing a lengthy prison sentence for drug possession charges, Ken Kesey faked a suicide attempt and fled to Mexico. The other Merry Pranksters soon went their separate ways as well. In 1968, Neal Cassady was found dead near some railroad tracks in Mexico.

Ken Kesey was eventually arrested for a relatively minor marijuana possession and given a six month sentence. The bus called Further was moved to Kesey’s home state of Oregon for safekeeping. Several Merry Pranksters have died since the 1960s, but Kesey continued to organize a series of reunions until his death from liver cancer surgery complications in 2001.



Captain Hank Quinlan, Owner and Publisher, Chief Curmudgeon
Captain Hank Quinlan, Owner and Publisher, Chief Curmudgeon with Sam Borsalino, Assistant Publisher

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Flatfoot  Willie, Corespondent at Large with fellow Staff Writers
Flatfoot Willie, Correspondent at Large with fellow Staff Writers

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May the Most Venerable H. L. Mencken bless our unworthy but earnest attempts at tongue in cheek jocularity .
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Latest office staff confab at Fat Bastard HQ.
Latest office staff confab at Fat Bastard HQ.

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