And so, we have the latest bill of goods diet/ ADHD pill, Vyvanse, on the market approved by the FDA. It seems to the Captain that Vyvanse is nothing more than a variation on the old amphetamine diet pills and methylphenidate ADHD pills with a much heftier price tag. Vyvanse has all the side effects of all the other amphetamines on the market and the captain bets that Vyvanse is no better or no worse than generic Ritalin (methylphenidate). These two chemical compounds are appetite suppressants, hence weight-loss: it really does not matter what overeating problem you have. What is not stated in the literature is the very insidious fact that you can get used to the effect of these pills as appetite suppressants and over eat anyway. You then experience all the side effects with none of the benefits. Especially deleterious to obese people are a tachycardia heart rate (heart rate above 90) and exacerbation of high blood pressure. It can also be stated that the weight gain normally experienced from over eating can be masked by the drug’s effect of increasing the metabolism rate. The rebound effects from going off the drug are immense, weight gain is increased at an accelerated rate, while the tachycardia and high blood pressure continue long after that drug use discontinued; sometimes necessitating the need for other drugs to compensate for these problems.
What then is the take away from all this? It appears that diets and exercise remain the best alternative to being overweight. Although studies have shown, and this is stated in an earlier edition of “The Fat Bastard Gazette” Bariatric Edition, over a long period of time weight gain is resumed at an increased rate. The answer appears then, at least for all obese people with a body mass index of 39 or greater, too seriously considered gastric surgery as a means to a permanent solution.
ABUSE AND DEPENDENCE
CNS stimulants (amphetamines and methylphenidate-containing products), including VYVANSE, have a high potential for abuse and dependence. Assess the risk of abuse prior to prescribing and monitor for signs of abuse and dependence while on therapy.
Table 3 : Adverse Reactions Reported by 2% or More of Adult Patients with ADHD Taking VYVANSE and at least Twice the Incidence in Patients Taking Placebo in a 4-Week Clinical Trial (Study 7)
|Increased Blood Pressure||3%||0%|
|Increased Heart Rate||2%||0%|
ADHD Drug Vyvanse may Treat Binge-Eating Disorder
A new research stated that drug Vyvanse meant to treat attention deficit/hyperactivity disorder (ADHD) might also help in treating binge-eating disorders.
The researchers said that when the drug is given at a higher dose then it can curtail excessive food consumption. The drug Vyvanse is the only approved drug in America to treat ADHD. It shall also be noted that for now, no drug has been approved for treating binge-eating disorder.
Also, it is now only that binge-eating has been classified as a disorder by the psychiatric community. Binge-eating disorder is generally associated with obese people. Main factors include food craving, repeated episodes of excessive food consumption, feeling of loss of control and psychological distress.
One of the study researchers, Dr. James Mitchell, President of the Neuropsychiatric Research Institute in Fargo said, “Presently, epilepsy drugs are commonly used to treat this disorder, and they actually do help the people to eat healthy and lose weight”.
But they also have side-effects that affect cognitive impairment and make it difficult for patients to cope from these medicines. In the 14-week long study, it has been found that the drug Vyvanse was quite effective in treating binge eating disorder and was also tolerated by most of the patients.
The trial was carried out on more than 500 adults having moderate to severe binge-eating disorder. In the trial, the researchers compared the ADHD drug lisdexamfetamine with a placebo from May 2011 to January 2012.
Study’s lead researcher Dr. Susan McElroy said that dosages were of 30, 50 or 70 mg/day or a placebo. It was found that a decline came in the number of binge-eating days per week in the groups taking 50mg and 70 mg doses daily in comparison to the placebo group. The study findings need to be replicated in larger groups of people with binge-eating disorder.
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All this and more always keeping our major focus on “Why so fat?” Enough said? We at “The Fat Bastard Gazette” think so. If you like what you read, and you know whom you are, in this yellow blog, tell your friends. We would be elated with an ever-wider readership. We remain cordially yours, Captain Hank Quinlan and the Monkeys in the back room
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